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pentobarbital will lessen the extent or impact of quetiapine by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Observe.pentobarbital will lower the extent or influence of diclofenac by affecting hepatic enzyme CYP2C9/ten metabolism. Minor/Significance Unknown.pentobarbital will lower the level or result of amiodarone by affectin